Product Details
BD Cytognos™
CD7
Human
Mouse IgG2a
Human hematopoietic progenitors, thymocytes, T cells, NK cells
5 µl/test
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
CE_IVD
cyt-7ap4 Rev. 1
Antibody Details
HULY-M2
CD7 is a 40KDa glycoprotein expressed on thymocytes, mature T cells, natural killer cells, pluripotent hematopoietic stem
cells, and progenitors of lymphoid and myeloid cells. CD7 is one of the earliest T-cell-specific antigens to be expressed in
lymphocytes, and the only early marker to persist throughout differentiation. Analysis of the expression of the CD7 antigen
as a T cell line marker, in combination with those CD3 and CD5 antigens, is useful in the diagnosis of T cell proliferative
syndromes such as T-ALL and T-prolymphocyte T cell leukaemias. The absence of expression of CD7, or its abnormal
expression, can provide useful information in the case of Sezary's syndrome or chronic lymphoid leukaemia. The CD7
antigen can be expressed by certain acute immature myeloid leukaemias.
cyt-7ap4 Rev. 1
Format Details
APC
Allophycocyanin (APC), is part of the BD family of phycobiliprotein dyes. This fluorochrome is a multimeric fluorescent phycobiliprotein with excitation maximum (Ex Max) of 651 nm and an emission maximum (Em Max) at 660 nm. APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
APC
651 nm
660 nm
cyt-7ap4 Rev.1
Citations & References
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cyt-7ap4 Rev. 1
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