HLA-DR-FITC

BD Cytognos™ HLA-DR-FITC

Name: HLA-DR-FITC
Brand: BD Cytognos™
SKU: cyt-drf2

Clone L243

(RUO)

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Product Details

Brand: BD Cytognos™

Alternative Name: MHC class II antigen; HLA class II histocompatibility antigen

Reactivity: Human

Isotype: Mouse IgG2a, κ

Immunogen: Human lymphoblastoid B-cell line RPMI 8866

Vol. Per Test: 5 µl/test

Entrez Gene ID: 3122, 3123, 3125, 3126, 3127

Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Regulatory Status: RUO

cyt-drf2 Rev. 1

Antibody Details

L243

The L243 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells including B cells, dendritic cells, monocytes, macrophages, Langerhans cells, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.

cyt-drf2 Rev. 1

Format Details

FITC

Fluorescein (FITC) is part of the BD blue family of dyes. This is a small organic fluorochrome with an excitation maximum (Ex Max) at 494-nm and an emission maximum (Em Max) at 518-nm. FITC is designed to be excited by the Blue laser (488-nm) and detected using an optical filter centered near 520 nm (e.g., a 530/30-nm bandpass filter). Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.

Format: FITC

Excitation Source: Blue 488 nm

Excitation Max: 494 nm

Emission Max: 518 nm

cyt-drf2 Rev.1

Citations & References

View product citations for antibody "cyt-drf2" on CiteAb

cyt-drf2 Rev. 1

Please refer to Support Documents for Quality Certificates

Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described

Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

BD Cytognos™ HLA-DR-FITC

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