Preparation And Storage
Store vials at 2° to 8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
CD30, clone Ber-H83, is derived from the hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immunized with Co cells. CD30 recognizes a 120-kilodalton (kd) type I transmembrane glycoprotein. The CD30 antigen belongs to the tumor necrosis factor receptor/nerve growth factor receptor (TNFR/NGFR) superfamily.
Development References (5)
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Chiarle R, Podda A, Prolla G, Gong J, Thorbecke GJ, Inghirami G. Molecule of the month: CD30 in normal and neoplastic cells. Clin Immunol. 1999; 90:157-164. (Biology).
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Dürkop H, Latza U, H S. Schlossman SF, Boumsell L, Gilks W, et al, ed. Leucocyte Typing V: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 1995:1115-1116.
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Jones DB, Cantarini M, Higginson K, Wright DH. Knapp W, Dörken B, Gilks WR, et al, ed. Leucocyte Typing IV: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 1989:478-479.
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Schwarting R, Stein H. Knapp W, Dörken B, Gilks WR, et al, ed. Leucocyte Typing IV: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 1989:419-421.
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Stein H, Mason DY, Gerdes J, et al. The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. Blood. 1985; 66:848-858. (Biology).
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