APC Mouse Anti-Human IREM-2

BD™ APC Mouse Anti-Human IREM-2

Name: APC Mouse Anti-Human IREM-2
Brand: BD™
SKU: 656158

Clone UP-H2 (also known as UP-H2)

(RUO)

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Product Details

Brand: BD™

Alternative Name: IREM-2

Reactivity: Human

Isotype: Mouse IgG1, κ

Application: Flow cytometry

Concentration: 25 μg/mL

Vol. Per Test: 5 μL

Entrez Gene ID: 342510

Regulatory Status: RUO

656158 Rev. 1

Antibody Details

UP-H2

The IREM-2 antibody, clone UP-H2, is derived from the hybridization of SP2 mouse myeloma cells with spleen cells from BALB/c mice immunized with 300.19 cells transfected with HA-tagged IREM-2.

The IREM-2 antibody recognizes a 34-kilodalton (kDa) integral membrane glycoprotein which is a member of the CMFRF35 subfamily of the immunoglobulin (Ig) superfamily. The IREM-2 antigen is also known as CD300e, CMRL35L1, LMIR6, and CLM-2.

656158 Rev. 1

Format Details

APC

Allophycocyanin (APC), is part of the BD family of phycobiliprotein dyes. This fluorochrome is a multimeric fluorescent phycobiliprotein with excitation maximum (Ex Max) of 651 nm and an emission maximum (Em Max) at 660 nm. APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.

Format: APC

Excitation Source: Red 627-640 nm

Excitation Max: 651 nm

Emission Max: 660 nm

656158 Rev.1

Citations & References

Development References (7)

Aguilar H, Alvarez-Errico D, García-Montero AC, Orfao A, Sayós J, López-Botet M. Molecular characterization of a novel immune receptor restricted to the monocytic lineage. J Immunol. 2004; 173(11):6703-6711. (Biology). View Reference
Brckalo T, Calzetti F, Pérez-Cabezas B, Borràs FE, Cassatella MA, López-Botet M. Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells.. Eur J Immunol. 2010; 40(3):722-32. (Biology). View Reference
Centers for Disease Control. Update: universal precautions for prevention of transmission of human immunodeficiency virus, hepatitis B virus, and other bloodborne pathogens in healthcare settings. MMWR. 1988; 37:377-388. (Biology).
Clinical and Laboratory Standards Institute. 2005. (Biology).
Hamerman JA, Ni M, Killebrew JR, Chu CL, Lowell CA. The expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.. Immunol Rev. 2009; 232(1):42-58. (Biology). View Reference
Zola H, Swart B, Nicholson I, Voss E. Leukocyte and Stromal Cell Molecules: The CD Markers. 2007. (Biology).
van Dongen JJ, Lhermitte L, Böttcher S, et al. EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes. Leukemia. 2012; 26(9):1908-1975. (Biology). View Reference

View All (7)

656158 Rev. 1

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Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described

Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Refer to manufacturer's instructions for use and related User Manuals and Technical Data Sheets before using this product as described.

Comparisons, where applicable, are made against older BD technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.