Stem Cell Research

Solutions from BD Biosciences

Human Mesenchymal Stem Cell Expansion

BD Mosaic™ Mesenchymal Stem Cell Serum-Free (MSC SF) is a complete, chemically defined expansion environment for human mesenchymal stem cells (hMSCs) that provides greater consistency than traditional methods at a lower cost. It is the first in a line of breakthrough next-generation cell culture environments for the expansion of stem cells to be used in cell therapy as well as basic and applied research.

Human Embryonic Stem Cell Expansion

BD Biosciences, StemCell Technologies, and the WiCell™ Research Institute have established a strategic collaboration to develop optimized, feeder-independent cell culture environments for human embryonic stem (hES) cell research, including serum-free defined media and qualified surfaces.

BD Biosciences offers BD Matrigel™ hESC qualified matrix. Each batch has been qualified with mTeSR™1, available from StemCell Technologies, thus eliminating the need for time-consuming screening, to provide the reproducibility and consistency essential for your hES cell research. The mTeSR1 formulation and BD Matrigel matrix have been shown to be a successful combination for culturing different WiCell hES cell lines for up to 20 passages. mTeSR1 and BD Matrigel hESC-qualified matrix, a high-quality medium and surface combination, create the first complete environment to support feeder-independent expansion of hES cells.

Additional Stem Cell Expansion Tools

BD offers a broad range of stem cell reagents for a variety of stem cell types, including extracellular matrix proteins, cytokines, and growth factors that facilitate consistent and reproducible results.

• BD provides reliable and consistent surfaces for cell culture and maintenance (BD Falcon™) and attachment and differentiation (BD BioCoat™).
• BD PureCoat™ amine and carboxyl surfaces are chemically-defined, animal-free enhanced cell culture surfaces that deliver high lot-to-lot consistency, translating to consistent and reproducible results in cell culture assays.
• BD PuraMatrix™ peptide hydrogel provides a versatile, optically clear 3D matrix, which has been used with neuronal and mesenchymal stem cells. Bone differentiation of mesenchymal stem cells has been studied on BD 3D Calcium Phosphate Scaffold, a rigid, pre-formed scaffold.