BD Cell Signaling Pathways
Tutorial
BD™ Cell Pathways makes it easy to find detailed information about a particular molecule.
The Ingenuity Knowledgebase includes manually curated findings from the full text of scientific publications, in addition to information from public gene databases. This convenient single reference source saves time by quickly bridging connections.
To begin, enter the molecule name in the main search box for bdbiosciences.com. The Entrez Gene ID number, the gene name symbol [BRCA1], or common synonyms can also be used. Molecules can also be found by querying terms in the names of pathways where the molecule participates. In this example, a search was performed for the STAT5 molecule using its Entrez Gene ID and name, “STAT5 or 20850.” BD has several antibodies to phosphorylated STAT5 that are displayed in the Products tab. Hovering over the molecule column for one of these products displays a pop-up window showing the related molecules found in the BD™ Cell Pathways tool.
A search for gene name and Entrez Gene ID
Clicking the highlighted molecule brings the user to a summary record for that molecule. The summary page provides the most current information on the molecule from the Ingenuity Knowledgebase. Researchers can review information integrated from public databases and manually curated findings from primary literature sources, including peer-reviewed journal articles, review articles, and textbooks. This information facilitates analysis of experimental data and enables the identification of relationships, mechanisms, functions, and pathways of relevance.
A gene summary page
This page includes:
- A summary description
- Molecules regulated by the gene, molecules that regulate the gene
- Binding partners, protein domains
- Role in the cell, associated diseases, molecular functions
- Biological processes and pathways
- Cellular components and subcellular locations
- Literature references
Additional gene information is available through quick links to Ingenuity's IPA software.
