BD Pathway bioimaging systems
BD Pathway Systems
The benchtop BD Pathway™ 435 and stand-alone BD Pathway™ 855 feature precision optics with flexible and easy-to-use controls and comprehensive acquisition and analysis software. Images are captured using a unique confocal spinning disk slider. The confocal mode enables a BD Pathway instrument to deliver high-resolution images without the background fluorescence often associated with widefield imaging systems. The laser-based autofocus capability of the BD Pathway systems enables rapid acquisition of high-quality images. The systems can also use camera-based autofocus or combined autofocus modes when more control over image acquisition is required.
The BD Pathway 435 system is a compact benchtop platform ideal for endpoint biological assays. Light from a mercury metal halide lamp introduced through a liquid light guide provides illumination from 360 nm to 700 nm. A transmitted light canopy provides the ability to capture bright-field images that can be overlaid onto fluorescent images. The lamp requires no light alignment and is rated to last 2000 hours.
BD Pathway 435 Benchtop System
The BD Pathway 435 system is a compact benchtop platform ideal for endpoint biological assays. Light from a mercury metal halide lamp introduced through a liquid light guide provides illumination from 360 nm to 700 nm. A transmitted light canopy provides the ability to capture bright-field images that can be overlaid onto fluorescent images. The lamp requires no light alignment and is rated to last 2000 hours.
The BD Pathway 855 system offers the ultimate in flexibility for high-content imaging of live and fixed cells. The dual-mercury metal halide lamps' long life and alignment-free illumination deliver imaging across the full spectrum from 340 nm to 750 nm. Researchers can select among 16 different excitation filters suited for a broad range of applications.
Equipped with environmental control and liquid handling, the system can perform a wide range of fluorescence-based kinetic and endpoint biological assays. A binocular eyepiece allows for direct viewing of cells in both fluorescence and transmitted light modes.
BD Pathway 855 Stand-Alone System
The BD Pathway 855 system offers the ultimate in flexibility for high-content imaging of live and fixed cells. The dual-mercury metal halide lamps' long life and alignment-free illumination deliver imaging across the full spectrum from 340 nm to 750 nm. Researchers can select among 16 different excitation filters suited for a broad range of applications.
Equipped with environmental control and liquid handling, the system can perform a wide range of fluorescence-based kinetic and endpoint biological assays. A binocular eyepiece allows for direct viewing of cells in both fluorescence and transmitted light modes.
Cell samples are prepared on multiwell plates, culture slides, or other imaging-compatible substrates.
Cell samples on 96-well plate
Cell samples are prepared on multiwell plates, culture slides, or other imaging-compatible substrates.
The BD Pathway captures images in either confocal or widefield mode, delivering the best possible analysis methods.
Image captured in confocal mode
The BD Pathway captures images in either confocal or widefield mode, delivering the best possible analysis methods.
The segmented image may be further divided into regions of interest (ROI) where fluorescence measurements are made. These measurements can include fluorescence intensity ratios, granularity, morphological features, fluorescence localization, and more.
ROI image
The segmented image may be further divided into regions of interest (ROI) where fluorescence measurements are made. These measurements can include fluorescence intensity ratios, granularity, morphological features, fluorescence localization, and more.
Individual cells can then be classified into different categories based on endpoint or kinetic response profiles at the cell, well, or plate level.
Cell categorization
Individual cells can then be classified into different categories based on endpoint or kinetic response profiles at the cell, well, or plate level.
Data is analyzed and presented within the provided software, or it can be exported for analysis within third-party software.
Data analysis
Data is analyzed and presented within the provided software, or it can be exported for analysis within third-party software.
Class I (1) laser product.
