ADME/Tox Research
Products
Metabolism Products
Drug metabolism plays a critical role in the toxicity, efficacy or detoxification of a drug compound. Understanding how a drug compounds' enzymatic metabolic pathways and metabolic rates influence its clearance, metabolite concentration, and potential drug-drug interactions is a critical component to developing safe and effective drugs.
BD Biosciences extensive portfolio of products and services to support the characterization of drug metabolism and drug-drug interactions include: recombinant drug metabolizing enzymes, human- and animal-derived hepatocytes and tissue fractions, antibodies, chemical substrates, metabolites and inhibitors needed to perform metabolic studies.
BD Gentest High Viability CryoHepatocyte Recovery Kit
The BD Gentest™ high viability cryohepatocyte recovery kit provides a high-viability, high-yield recovery medium optimized for a single centrifugation step as well as an optimized plating medium for high plating efficiency.
BD Tissue Fractions - Reagents for Drug Metabolism
Tissue fractions from human and animal livers represent an imporant tool in preclinical metabolism studies for predicting the toxicity and pharmacokinetic properties of a drug compound.
Antibodies Against Drug Metabolizing Enzymes
BD Supersomes Recombinant Drug Metabolizing Enzymes and Controls
- Animal Cytochrome P450 Enzymes
- Control Supersomes Enzymes, NADPH, UDPGA and Incubation Buffers
- Fluorometric Cytochrome P450 Inhibition Kits
- Human Cytochrome P450 Enzymes
- UGT and Other Metabolic Enzymes
Enzyme Substrates, Inhibitors, Metabolite Standards, Cofactors and Buffers
- Cytochrome P450 and UGT Substrates, Metabolite Standards and Inhibitors
- Fluorometric Substrates and Associated Metabolite Standards
- NADPH, UDPGA and Incubation Buffers
- Stable Isotope Labeled Reference Metabolites
Primary Hepatocytes
- Animal CryoHepatocytes
- Hepatocyte Purification and Culture
- Human CryoHepatocytes
- Human Fresh Hepatocytes
Tissue Fractions
- Animal Liver Microsomes, S9, and Cytosol
- Human Pooled Liver Microsomes, S9, and Cytosol
- Human Single Donor Liver Microsomes Including Allelic Variants
- NADPH, UDPGA and Incubation Buffers
- Tissue Fractions Prepared From Extrahepatic Tissue
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
