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BD Falcon™ TufRol™ EZ Roller Bottles

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The BD Falcon™ TufRol™ EZ Roller Bottle offers a unique new way to manipulate roller bottles. The EZ Grip, a deep indentation in the bottom of the bottle, creates a handhold for easier pouring. Sloped shoulders allow for greater volume recovery when pouring. In addition, the neck and cap design ensures a secure seal with minimal torque.

Like the current BD Falcon roller bottles, the new BD Falcon™ TufRol™ EZ has a one-piece design. While polystyrene does not normally offer high-impact resistance, the BD Falcon roller bottles are manufactured using a proprietary manufacturing process that provides good impact resistance. This inherent high-strength feature reduces the risk of messy spills and loss of precious contents during accidental mishandling.

BD Falcon™ TufRol™ EZ Roller Bottles are tissue-culture treated, nonpyrogenic, and sterilized by gamma irradiation. As with most BD Falcon™ products, our roller bottles are manufactured under a registered ISO 9002 Quality System.

Automated and Manual Lab Friendly
The one-piece design of BD Falcon™ TufRol™ EZ Roller Bottle is compatible with manual or automated filling systems. Bottles with or without the EZ Grip indentation are available.

Custom Products
Since many industrial customers have special requirements relative to labeling, lot control, packaging configurations, and delivery schedules, BD Biosciences develops custom services and products to suit individual needs. As with all our products, certification is available on request.

Benefits of BD™ Cell in Roller Bottle Production

Yield of BD™ Cell Using Protein-G purification

[Click Image to Enlarge ]
First evaluated in roller bottles, BD™ Cell has proven itself a worthy alternative to traditional basal media. While a standard method of culturing antibody, roller bottle production has some limitations: extensive labor and frequent feedings. The initial roller bottle evaluation compared BD Cell™ MAb Medium (basal) with Iscove‘s Modified Dulbecco‘s Medium (IMDM) both supplemented with 10 percent fetal bovine serum (FBS). The cultures were inoculated at a density of 2 x 105 cells/ml. The IMDM was run conventionally with harvesting and feeding performed every two to three days. By contrast, the BD™ Cell culture was run batch fed and incubated untouched for 21 days. Now evaluated in a production environment on more than 300 hybridoma lines, BD Cell‘s average increase of antibody yield 8 to 10 times that of classic IMDM media. Benefits of BD Cell™ MAb Media

Advantages

  • A novel indentation in the bottom, similar to the punt on a wine bottle, creates a comfortable and convenient bottom grip
  • EZ Twist Caps spin smoothly and securely onto the bottles
  • Angled shoulders allow for better product recovery when pouring
  • Proprietary bottle manufacturing process provides greater impact resistance
  • Custom packaging, labeling, and lot control available on request.
  • Tissue-culture treated by vacuum gas plasma for consistent cell attachment
  • Manufactured in a class 100,000 clean room under a registered ISO 9002 Quality System
  • Multiple choices to meet your application needs
  • Available with deep indent or no bottom grip, standard or vented cap

Technical Documents

  • BD Falcon™ TufRol™ EZ Roller Bottles--Product Sheet [ PDF ]
  • BD Falcon™ Cell Culture Products [ PDF ]
  • BD Falcon™ TufRol™ Roller Bottles & BD Cell™ MAb Medium [ PDF ]
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