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ADME/Tox Source

BD Gentest Metabolism Products

Metabolism Products and Services

Drug metabolism plays a critical role in the toxicity and efficacy or detoxification of a drug compound. Understanding how a drug compound’s enzymatic metabolic pathways and metabolic rates influence its clearance, metabolite concentration and potential drug-drug interactions is a critical component to developing safe and effective drugs.

BD Biosciences portfolio of products and Contract Research Services which support the characterization of drug metabolism and drug-drug interactions include: recombinant drug metabolizing enzymes, human and animal derived hepatocytes and tissue fractions, antibodies, chemical substrates, and inhibitors needed to perform metabolic studies.

Physiologically Relevant

BD Gentest's in vitro models simulate in vivo metabolite profiles and metabolizing enzyme activities.

Lot-to-lot Consistency

Low lot-to-lot product variability assures consistent data comparisons today and tomorrow.

Extensive Portfolio

Full complement of products and services to accommodate your needs for drug metabolism and drug-drug interaction testing.

 

BD Supersomes™ P450/UGT and Other Metabolic Enzymes

Tissue Fractions

Primary Hepatocytes

Substrates, Inhibitors, Metabolite Standards, Solutions

Related Products

Contract Research Services

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