Enzyme Induction Studies
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In vitro models using human hepatocytes can predict the potential of drug candidates to be enzyme inducers. Induction in preclinical species can shed light on the results of animal pharmacokinetic studies and may be predictive of tumorigenicity.
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Services
BD GentestSM Contract Research Services Human hepatocyte models include:
FDA-sponsored guidance documents
BD Biosciences offers several state-of-the-art induction testing methods that adhere to applicable FDA-sponsored guidance documents.
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Consult the ADME Experts
Call 888.334.5229, ext. 2246, to discuss your contract needs. Customers outside the U.S. may reach us at 781.935.5115, ext. 2246. |